Human Glypican 1/GPC1 Protein (GPC-HM111)
$283.50 – $945.00
KACTUS Biosystems Human Glypican 1/GPC1 Protein (GPC-HM111) (catalog No. GPC-HM111) is expressed from HEK293 with His tag at the C-Terminus.It contains Asp24-Ser530.
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| Catalog No. | GPC-HM111 |
|---|---|
| Product Name | Human Glypican 1/GPC1 Protein (GPC-HM111) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Glypican-1; FLJ38078; GPC1 |
| Species | Human |
| Source | HEK293 |
| Accession | P35052-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Asp24-Ser530 |
| Molecular Weight | The protein has a predicted MW of 57.1 kDa. Due to glycosylation, the protein migrates to 70-135 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
GPC-HM111: Human Glypican 1/GPC1 Protein (GPC-HM111)
CAR-T cells targeting glypican-1 (GPC1)-specific human and murine CAR-T cells generated from our original anti-human/mouse GPC1 antibody showed strong antitumor effects in xenogeneic and syngeneic mouse models, respectively. Importantly, the murine CAR-T cells enhanced endogenous T cell responses against a non-GPC1 tumor antigen through the mechanism of antigen-spreading and showed synergistic antitumor effects with anti-PD-1 antibody without any adverse effects in syngeneic models.
Please remember our product information: Human Glypican 1/GPC1 Protein (GPC-HM111) catalog number: GPC-HM111 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |