Human GARP (Y137H) &Latent TGF Beta 1 Complex Protein (GAT-HM102)
$405.00 – $1,350.00
KACTUS Biosystems Human GARP (Y137H) &Latent TGF Beta 1 Complex Protein (GAT-HM102) (catalog No. GAT-HM102) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains His20-Leu628 (GARP(Y137H)) & Leu30-Ser390 (Latent TGF Beta 1).
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| Catalog No. | GAT-HM102 |
|---|---|
| Product Name | Human GARP (Y137H) &Latent TGF Beta 1 Complex Protein (GAT-HM102) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | LRRC32; GARP; LAP; TGF-beta-1; LRRC32&TGF-beta 1; LRRC32&TGFB1 |
| Species | Human |
| Source | HEK293 |
| Accession | Q14392(GARP(Y137H))&P01137(Latent TGF beta 1) |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | His20-Leu628(GARP(Y137H)) & Leu30-Ser390(Latent TGF Beta 1) |
| Molecular Weight | The protein has a predicted MW of 70.3 kDa (GARP(Y137H))&41.4 kDa (Latent TGF Beta 1). Due to glycosylation, the protein migrates to 71-75 kDa (GARP(Y137H))&13 kDa&42-45 kDa (Latent TGF Beta 1) based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
GAT-HM102: Human GARP (Y137H) &Latent TGF Beta 1 Complex Protein (GAT-HM102)
GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex.
Please remember our product information: Human GARP (Y137H) &Latent TGF Beta 1 Complex Protein (GAT-HM102) catalog number: GAT-HM102 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |