Human EGFRVIII Protein (EG8-HM154)
$270.00 – $900.00
KACTUS Biosystems Human EGFRVIII Protein (EG8-HM154) (catalog No. EG8-HM154) is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Leu25-Ser378.
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| Catalog No. | EG8-HM154 |
|---|---|
| Product Name | Human EGFRVIII Protein (EG8-HM154) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | ErbB; EC 2.7.10; EC 2.7.10.1; EGFR; mENA; LEGFR; ERBB; ERBB1; HER1; PIG61; NISBD2 |
| Species | Human |
| Source | HEK293 |
| Accession | NP_001333870.1 |
| Product Tag | C-His-Avi |
| Biotinylated | no |
| Exact Sequence | Leu25-Ser378 |
| Molecular Weight | The protein has a predicted MW of 41.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
EG8-HM154: Human EGFRVIII Protein (EG8-HM154)
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with EGFR gene amplification frequently contain EGFR gene rearrangements, with the most common extracellular domain mutation being EGFRvIII. This mutation leads to a deletion of exons 2-7 of the EGFR gene and renders the mutant receptor incapable of binding any known ligand.
Please remember our product information: Human EGFRVIII Protein (EG8-HM154) catalog number: EG8-HM154 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |