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Human CTLA-4/CD152 Protein (CTL-HM241)

Human CTLA-4/CD152 Protein (CTL-HM241)

Human CTLA-4/CD152 Protein (CTL-HM241)

$101.70$337.50

In stock

$101.70$337.50

KACTUS Biosystems Human CTLA-4/CD152 Protein (CTL-HM241) (catalog No. CTL-HM241) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys36-Asp161.

SKU: CTL-HM241
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Catalog No. CTL-HM241
Product NameHuman CTLA-4/CD152 Protein (CTL-HM241)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms CTLA4; CD152; ICOS; CELIAC3; GRD4; GSE; ALPS5; IDDM12
Species Human
Source HEK293
Accession P16410-1
Product Tag C-hFc
Biotinylated no
Exact Sequence Lys36-Asp161
Molecular Weight The protein has a predicted MW of 40.1 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

CTL-HM241: Human CTLA-4/CD152 Protein (CTL-HM241)

CTLA-4 (cytotoxic T-lymphocyte-associated protein 4), also known as CD152, is a protein receptor that, functioning as an immune checkpoint, downregulates immune responses.CTLA4 is constitutively expressed in regulatory T cells but only upregulated in conventional T cells after activation – a phenomenon which is particularly notable in cancers. It acts as an “off” switch when bound to CD80 or CD86 on the surface of antigen-presenting cells.

Please remember our product information: Human CTLA-4/CD152 Protein (CTL-HM241) catalog number: CTL-HM241 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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