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Human CD96/TACTILE Protein (CD9-HM196)

Human CD96/TACTILE Protein (CD9-HM196)

Human CD96/TACTILE Protein (CD9-HM196)

$310.50$1,035.00

In stock

$310.50$1,035.00

KACTUS Biosystems Human CD96/TACTILE Protein (CD9-HM196) (catalog No. CD9-HM196) is expressed from HEK293 with His tag at the C-Terminus.It contains Val22-Met503.

SKU: CD9-HM196
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Catalog No. CD9-HM196
Product NameHuman CD96/TACTILE Protein (CD9-HM196)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms CD96 molecule; CD96; DKFZp667E2122; TACTILE
Species Human
Source HEK293
Accession P40200-2
Product Tag C-His
Biotinylated no
Exact Sequence Val22-Met503
Molecular Weight The protein has a predicted MW of 54.7 kDa. Due to glycosylation, the protein migrates to 115-130 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

CD9-HM196: Human CD96/TACTILE Protein (CD9-HM196)

The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells, and recent studies suggest both play important inhibitory roles in immune function. CD96 has been shown to modulate immune cell activity in mice, with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance. The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor, CD226, offers unique strategies for immuno-oncology drug development.

Please remember our product information: Human CD96/TACTILE Protein (CD9-HM196) catalog number: CD9-HM196 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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