Human CD45/PTPRC Protein (PTP-HM204)
$283.50 – $945.00
KACTUS Biosystems Human CD45/PTPRC Protein (PTP-HM204) (catalog No. PTP-HM204) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Lys577.
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| Catalog No. | PTP-HM204 |
|---|---|
| Product Name | Human CD45/PTPRC Protein (PTP-HM204) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | P08575-3 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Gln26-Lys577 |
| Molecular Weight | The protein has a predicted MW of 87.53 kDa. Due to glycosylation, the protein migrates to 120-160 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PTP-HM204: Human CD45/PTPRC Protein (PTP-HM204)
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts.
Please remember our product information: Human CD45/PTPRC Protein (PTP-HM204) catalog number: PTP-HM204 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |