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Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240)

Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240)

Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240)

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KACTUS Biosystems Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240) (catalog No. CDL-HM240) is expressed from HEK293 with monomeric hFc tag at the N-Terminus.It contains Met113-Leu261.

SKU: CDL-HM240
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Catalog No. CDL-HM240
Product NameHuman CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms CD40L; CD40LG; CD154; TNFSF5; TNFSF5IMD3; CD40LIGM; gp39; HIGM1; T-BAM; TRAP; IGM; IMD3; CD40 Ligand
Species Human
Source HEK293
Accession P29965
Product Tag N-monomeric hFc
Biotinylated no
Exact Sequence Met113-Leu261
Molecular Weight The protein has a predicted MW of 74.9 kDa. Due to glycosylation, the protein migrates to 75-80 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.; -20 to -80°C for 3-6 months in unopened state after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

CDL-HM240: Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240)

CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. .

Please remember our product information: Human CD40 Ligand/TNFSF5 Trimer Protein (CDL-HM240) catalog number: CDL-HM240 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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