Human CD37 Protein (CD3-HM137)
$283.50 – $945.00
KACTUS Biosystems Human CD37 Protein (CD3-HM137) (catalog No. CD3-HM137) is expressed from HEK293 with His tag at the C-Terminus.It contains Ala113-Asn240.
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| Catalog No. | CD3-HM137 |
|---|---|
| Product Name | Human CD37 Protein (CD3-HM137) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | P11049-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Ala113-Asn240 |
| Molecular Weight | The protein has a predicted MW of 15.72 kDa. Due to glycosylation, the protein migrates to 25-40 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CD3-HM137: Human CD37 Protein (CD3-HM137)
CD37 is a tetraspanin expressed prominently on the surface of B cells. It is an attractive molecular target exploited in the immunotherapy of B cell-derived lymphomas and leukemia. Currently, several monoclonal antibodies targeting CD37 as well as chimeric antigen receptor-based immunotherapies are being developed and investigated in clinical trials. Given the unique role of CD37 in the biology of B cells, it seems that CD37 constitutes more than a docking point for monoclonal antibodies, and targeting this molecule may provide additional benefit to relapsed or refractory patients.
Please remember our product information: Human CD37 Protein (CD3-HM137) catalog number: CD3-HM137 KACTUS Biosystems