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Human AREG Protein (AEG-HM201)

Human AREG Protein (AEG-HM201)

Human AREG Protein (AEG-HM201)

$270.00$900.00

In stock

$270.00$900.00

KACTUS Biosystems Human AREG Protein (AEG-HM201) (catalog No. AEG-HM201) is expressed from HEK293 with hFc tag at the N-Terminus.It contains Ser101-Lys187.

SKU: AEG-HM201
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Catalog No. AEG-HM201
Product NameHuman AREG Protein (AEG-HM201)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms Amphiregulin; AR; SDGF; AREG; AREGB; CRDGF; MGC13647
Species Human
Source HEK293
Accession P15514
Product Tag N-hFc
Biotinylated no
Exact Sequence Ser101-Lys187
Molecular Weight The protein has a predicted MW of 37.3 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

AEG-HM201: Human AREG Protein (AEG-HM201)

Amphiregulin (AREG) is a member of the epidermal growth factor (EGF) family and is expressed in a plethora of cancers. Tumour growth and metastasis were decreased by AREG silencing in an orthotopic model of pancreatic cancer. AREG may play a critical role in cell migration, invasion, and EMT by activating the EGFR/ERK/NF‑κB signalling pathway in pancreatic cancer cells.
Please remember our product information: Human AREG Protein (AEG-HM201) catalog number: AEG-HM201 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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