GDC-0068

Description

Background Information:

GDC-0068 is a potent, APT-competitive and orally available small
molecule pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2
and Akt3, respectively, and with selectivity over more than other 200
screened kinases. It displays robust antitumor activity with activated
PI3K-Akt-mTOR pathway, and is currently in clinical trials.

APIM050149: GDC-0068

CAS No.: 1001264-89-6.
Molecular Formula: C₂₄H₃₂ClN₅O₂?1.6HCl.
Molecular Weight: 520.
Purity: 99% chem and stereomeric purity (HPLC and Chiral HPLC).
QC: HPLC-MS, ¹HNMR, Chiral HPLC, and Quantitative Elemental Analysis.
Solubility: Soluble in DMSO.
Storage: Store at 0°C (short term), -20°C (long term), desiccated.

Additional information

Ship from Country	USA
Size	10 mg, 100 mg, 200 mg, 5 mg, 50 mg

No more offers for this product!