GCLC Rabbit mAb
$148.00 – $548.00
GCL; GCS; GLCL; GLCLC
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| Catalog No. | A4499 |
|---|---|
| Product Name | GCLC Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | GCL; GCS; GLCL; GLCLC |
| Gene Name | GCLC |
| Protein Name | GCLC |
| Uniprot/Swissprot ID | P48506 |
| Gene ID | 2729 |
| Clone | ARC1065 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Rat |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase is the first rate-limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. This locus encodes the catalytic subunit, while the regulatory subunit is derived from a different gene located on chromosome 1p22-p21. Mutations at this locus have been associated with hemolytic anemia due to deficiency of gamma-glutamylcysteine synthetase and susceptibility to myocardial infarction.
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