Epitope Binning Service
Epitope binning, a competitive immunoassay, investigates the sequential binding of two antibodies to an antigen. Information from epitope binning broadens intellectual property protection.
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| Catalog No. | BS088 |
|---|---|
| Product Name | Epitope Binning Service |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Summary | Epitope binning, a competitive immunoassay, investigates the sequential binding of two antibodies to an antigen. Information from epitope binning broadens intellectual property protection. |
| Order Offline | Phone: 1-617-401-8149Fax: 1-617-606-5019Email: message@sydlabs.comOr leave a message with a formal purchaseorder (PO) Or credit card. |
Description
Epitope binning, a competitive immunoassay, is used to investigate the sequential binding of two antibodies to an antigen. Using the biolayer interferometry (BLI) platform, antibodies are tested in pairs to determine the ability of an antibody to block another’s binding to the antigen. A blocking profile is created for each antibody against all other antibodies in the library. Antibodies with similar blocking profiles are grouped into a bin, indicating these antibodies bind to the same or overlapping epitopes.
Information obtained by epitope binning is helpful to broaden intellectual property protection.
Antibody epitope binning service
Antigen is immobilized onto a BLI sensor using an appropriate method. Antibody 1 is allowed to saturate its epitope on the antigen. Binding of Antibody 2 to antigen saturated with Antibody 1 is assessed.
Materials needed:
– 100 ug each of purified antibody;
– 100 ug of purified antigen.
Fast turnaround:
2-3 weeks.
Deliverable:
Study report.
Additional information
| Ship from Country | USA |
|---|---|
| Size | 1 package |