Denosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant

Denosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant

$375.00

In stock

$375.00

Denosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant. Denosumab biosimilar CHO stable cell line is available for licensing to manufacture the denosumab biosimilar protein.The research grade denosumab biosimilar protein is for research use only (RUO). Recombinant human IgG2 isotype controls are available.

SKU: C004P.LA
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Catalog No. C004P.LA
Product NameDenosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant
Supplier Name Syd Labs, Inc.
Brand Name Syd Labs
Synonyms Anti-RANKL Human Monoclonal Antibody
Summary Recombinant Humanized IgG2 Monoclonal Antibody.
Isotype Human IgG1 kappa.
Source/Host The monoclonal antibody denosumab biosimilar was produced in the denosumab biosimilar CHO stable cell line.
Specificity/Sensitivity The monoclonal antibody denosumab biosimilar specifically binds to the human RANKL (RANK ligand) protein.
Form Of Antibody 0.2 uM filtered solution, pH 5.2, no stabilizers or preservatives.
Endotoxin < 1 EU per 1 mg of the protein by the LAL method.
Purity >95% by SDS-PAGE under reducing conditions and HPLC.
Shipping The Denosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant is shipped with ice pack. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70°C as supplied. 1 month from date of receipt, 2 to 8°C as supplied.
Note Denosumab biosimilar CHO stable cell line is available for licensing to manufacture the denosumab biosimilar protein.The research grade denosumab biosimilar protein is for research use only (RUO). Recombinant human IgG2 isotype controls are available.
Order Offline Phone: 1-617-401-8149 Fax: 1-617-606-5022 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card.

Description

C004P.LA: Denosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant

Recombinant Humanized IgG2 Monoclonal Antibody.

Background

Denosumab, a fully human monoclonal antibody, inhibits the RANKL (RANK ligand) protein, the primary signal for bone removal. Denosumab can be used for the treatment of osteoporosis, treatment-induced bone loss, bone metastases, multiple myeloma, and giant cell tumor of bone.

Syd Labs also provides the following research grade antibody biosimilar proteins:
Bevacizumab Biosimilar, research grade (VEGF-A)
Ranibizumab Biosimilar, research grade (VEGF-A, Fab produced in E. coli)
Cetuximab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Panitumumab Biosimilar, research grade (HER1, ErbB-1, EGFR)
Trastuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Pertuzumab Biosimilar, research grade (HER2, ErbB-2, c-neu)
Infliximab biosimilar, research grade (TNF alpha)
Adalimumab biosimilar, research grade (TNF alpha)
Rituximab biosimilar, research grade (CD20)
Denosumab biosimilar, research grade (RANKL, RANK ligand, OPGL, TNFSF11, CD254, TRANCE, ODF)
Palivizumab Biosimilar, research grade (RSV)
Omalizumab biosimilar, research grade (IgE)
Eculizumab biosimilar, research grade (C5)

Please remember our product information: Denosumab Biosimilar, L234A L235A P329G (LALAPG) Fc Silent Mutant: C004P.LA Syd Labs

Additional information

Ship from Country

USA

Size

0.5 mg

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