Cynomolgus TNFR2/CD120b/TNFR1B Protein (TNF-CM1R2)
$216.00 – $720.00
KACTUS Biosystems Cynomolgus TNFR2/CD120b/TNFR1B Protein (TNF-CM1R2) (catalog No. TNF-CM1R2) is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Asp257.
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| Catalog No. | TNF-CM1R2 |
|---|---|
| Product Name | Cynomolgus TNFR2/CD120b/TNFR1B Protein (TNF-CM1R2) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD120b; Etanercept; p75TBPII; p75TNFR; TNF RII; TNF-R2; TNF-R75; TNFR80; TNFRSF1B; TNFR2; TBPII; TNFBR; TNFR1B |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | A0A2K5VEV7 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Leu23-Asp257 |
| Molecular Weight | The protein has a predicted MW of 26.1 kDa. Due to glycosylation, the protein migrates to 49-60 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TNF-CM1R2: Cynomolgus TNFR2/CD120b/TNFR1B Protein (TNF-CM1R2)
Tumor Necrosis Factor Receptor II (TNF RII), also known as TNFRSF1B, p75/p80, and CD120b, is a type I transmembrane protein that belongs to the TNF receptor superfamily. It has a molecular weight of approximately 75 kDa.Receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha. Isoform 2 blocks TNF-alpha-induced apoptosis, which suggests that it regulates TNF-alpha function by antagonizing its biological activity.
Please remember our product information: Cynomolgus TNFR2/CD120b/TNFR1B Protein (TNF-CM1R2) catalog number: TNF-CM1R2 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |