Cynomolgus Tim-3/HAVCR2 Protein (TIM-CM131)
$283.50 – $945.00
KACTUS Biosystems Cynomolgus Tim-3/HAVCR2 Protein (TIM-CM131) (catalog No. TIM-CM131) is expressed from HEK293 with His tag at the C-Terminus.It contains Ser22-Arg201.
- Details & Specifications
- References
| Catalog No. | TIM-CM131 |
|---|---|
| Product Name | Cynomolgus Tim-3/HAVCR2 Protein (TIM-CM131) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | EHH54703.1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Ser22-Arg201 |
| Molecular Weight | The protein has a predicted MW of 20.8 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TIM-CM131: Cynomolgus Tim-3/HAVCR2 Protein (TIM-CM131)
Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
Please remember our product information: Cynomolgus Tim-3/HAVCR2 Protein (TIM-CM131) catalog number: TIM-CM131 KACTUS Biosystems