Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM301)
$243.00 – $810.00
KACTUS Biosystems Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM301) (catalog No. DKK-CM301) is expressed from HEK293 with mFc (IgG1) tag at the C-Terminus.It contains Thr32-His266.
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| Catalog No. | DKK-CM301 |
|---|---|
| Product Name | Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM301) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Cynomolgus/Rhesus macaque |
| Source | HEK293 |
| Accession | XP_005565907.1/NP_001247454.1 |
| Product Tag | C-mFc |
| Biotinylated | no |
| Exact Sequence | Thr32-His266 |
| Molecular Weight | The protein has a predicted MW of 51.42 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
DKK-CM301: Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM301)
Dickkopf related protein 1 (Dkk-1) is the founding member of the Dickkopf family of proteins that includes Dkk-1, -2, -3, -4, and a related protein, Soggy. Dkk proteins are secreted proteins that contain two conserved cysteine-rich domains separated by a linker region. Dkk antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation.
Please remember our product information: Cynomolgus/Rhesus macaque DKK1 Protein (DKK-CM301) catalog number: DKK-CM301 KACTUS Biosystems
