Cynomolgus LILRA4/CD85g Protein (LIL-CM1A4)
$243.00 – $810.00
KACTUS Biosystems Cynomolgus LILRA4/CD85g Protein (LIL-CM1A4) (catalog No. LIL-CM1A4) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu24-Asn446.
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| Catalog No. | LIL-CM1A4 |
|---|---|
| Product Name | Cynomolgus LILRA4/CD85g Protein (LIL-CM1A4) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD85g; ILT7; ILT-7; ILT7MGC129598; LILRA4; MGC129597 |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | XP_005590346.1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Glu24-Asn446 |
| Molecular Weight | The protein has a predicted MW of 47.7 kDa. Due to glycosylation, the protein migrates to 58-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
LIL-CM1A4: Cynomolgus LILRA4/CD85g Protein (LIL-CM1A4)
LILRA4, also known as ILT7 and CD85g, is an approximately 60-70 kDa variably glycosylated transmembrane protein that regulates immune cell activation. Mature human LILRA4 consists of a 423 amino acid (aa) extracellular domain (ECD) with four immunoglobulin-like domains, a 21 aa transmembrane segment, and a 32 aa cytoplasmic domain.LILRA4 function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G (PubMed:16735691, PubMed:19564354). Down-regulates the production of IFNA1, IFNA2, IFNA4, IFNB1 and TNF by plasmacytoid dendritic cells that have been exposed to influenza virus or cytidine-phosphate-guanosine (CpG) dinucleotides, indicating it functions as negative regulator of TLR7 and TLR9 signaling cascades.
Please remember our product information: Cynomolgus LILRA4/CD85g Protein (LIL-CM1A4) catalog number: LIL-CM1A4 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
