CXCR3 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

CXCR3 Rabbit mAb

$148.00$548.00

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$148.00$548.00

GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R

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SKU: A11294 Categories: ,
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Catalog No. A11294
Product NameCXCR3 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms GPR9; MigR; CD182; CD183; Mig-R; CKR-L2; CMKAR3; IP10-R
Gene Name CXCR3
Protein Name CXCR3
Uniprot/Swissprot ID P49682
Entrez GeneID 2833
Clone ARC0570
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716).

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