CEP43 Rabbit mAb
$148.00 – $548.00
FOP; FGFR1OP
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| Catalog No. | A21074 |
|---|---|
| Product Name | CEP43 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | FOP; FGFR1OP |
| Gene Name | CEP43 |
| Protein Name | CEP43 |
| Uniprot/Swissprot ID | O95684 |
| Gene ID | 11116 |
| Clone | ARC2913 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Reactivity | Human, Mouse |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
This gene encodes a largely hydrophilic centrosomal protein that is required for anchoring microtubules to subcellular structures. A t(6;8)(q27;p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn’s disease, Graves’ disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.
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