CD4 Unconjugated(112001)

CD4 Unconjugated(112001) catalog number: 112001 Caprico Biotechnologies

CD4 Unconjugated(112001)

$110.00$390.00

In stock

$110.00$390.00

Caprico Biotechnologies CD4 Unconjugated catalog number: 112001,The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily.

SKU: 112001
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Catalog No. 112001
Product NameCD4 Unconjugated(112001)
Supplier Name Caprico Biotechnologies, Inc.
Brand Name Caprico
Accession No. NM_000616.4
Protein Name CD4
Uniprot/Swissprot ID P01730
Entrez GeneID 920
Primary/Secondary Primary
Clone SK3
Clonality Monoclonal
Source/Host Mouse
Applications FC
Reactivity Cynomolgus monkey, Human, Rhesus
Immunogen Human peripheral blood T cells
Form Of Antibody PBS pH 7.2, 0.1% (w/v) BSA, 0.09% (w/v) sodium azide
Conjugate Unconjugated
Purity >95%
Stability & Storage 2-8oC
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Description

112001:CD4 Unconjugated(112001)

The clone SK3, a mouse monoclonal antibody selectively binds with a 55-59kD type I transmembrane glycoprotein and a member of the immunoglobulin superfamily. CD4 contains four extracellular Ig-like domains (D1-D4). The epitope for SK3 is located within the D3 domain of the protein, which has a structure resembling an Ig variable domain. Expression of CD4 is observed in subsets of T lymphocytes, monocytes, macrophages, and dendritic cells. Through interaction of MHC-II, CD4 facilitates cell-cell interaction, thymic differentiation, and activation of downstream signaling cascades. HIV infection of T-cells is instigated through binding of HIV to CD4. Binding of SK3 antibody blocks HIV infection through CD4 and also blocks the mixed lymphocyte reaction (MLR).
Please remember our product information: CD4 Unconjugated(112001) catalog number: 112001 Caprico Biotechnologies

Additional information

Ship from Country

USA

Size

100 μg

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