CD276 Biotin(112851)
$170.00
Caprico Biotechnologies CD276 Biotin catalog number: 112851，The clone 8G10, a mouse monoclonal antibody selectively binds with a 50-55 kD cell surface protein commonly known as Programmed cell death 1 (PD-1) or CD279, a member of the immunoglobulin superfamily.
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| Catalog No. | 112851 |
|---|---|
| Product Name | CD276 Biotin(112851) |
| Supplier Name | Caprico Biotechnologies, Inc. |
| Brand Name | Caprico |
| Accession No. | NC_000015.10 |
| Protein Name | CD276 |
| Uniprot/Swissprot ID | Q5ZPR3 |
| Gene ID | 80381 |
| Primary/Secondary | Primary |
| Clone | DCN.70 |
| Clonality | Monoclonal |
| Source/Host | Mouse |
| Reactivity | Human |
| Immunogen | Human Dendritic Cells |
| Form Of Antibody | PBS pH 7.2, 0.09% sodium azide |
| Conjugate | Biotin |
| Purity | >95% |
| Stability & Storage | 2-8oC |
| Note | Products will be shipped from the warehouse in Georgia. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Phone: 1-617-401-8149 Fax: 1-617-606-5061 Email: message@sydlabs.com Orleave a message with a formal purchase order (PO) Or credit card. |
Description
112851：CD276 Biotin(112851)
The clone 8G10, a mouse monoclonal antibody selectively binds with a 50-55 kD cell surface protein commonly known as Programmed cell death 1 (PD-1) or CD279, a member of the immunoglobulin superfamily. PD-1 expression is mostly observed in activated T cells and B cells, and also in dendritic cells. PD-1 signals via binding its two ligands, PD-L1 and PD-L2. Upon ligand binding, PD-1 signaling inhibits T-cell activation, leading to reduced proliferation, cytokine production, and T cell death. Blocking of PD-1 by its antibody restores T cells immunity against tumor and infectious agents. PD-1-blockade based immunotherapy is, therefore, highly clinically useful against various types of cancers and infectious diseases.
Please remember our product information: CD276 Biotin(112851) catalog number: 112851 Caprico Biotechnologies