Canine CD40/TNFRSF5 Protein (CD4-DM140)
$283.50 – $945.00
KACTUS Biosystems Canine CD40/TNFRSF5 Protein (CD4-DM140) (catalog No. CD4-DM140) is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Ala194.
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| Catalog No. | CD4-DM140 |
|---|---|
| Product Name | Canine CD40/TNFRSF5 Protein (CD4-DM140) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Canine |
| Source | HEK293 |
| Accession | Q7YRL5 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Glu21-Ala194 |
| Molecular Weight | The protein has a predicted MW of 20.14 kDa. Due to glycosylation, the protein migrates to 30-40 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
CD4-DM140: Canine CD40/TNFRSF5 Protein (CD4-DM140)
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
Please remember our product information: Canine CD40/TNFRSF5 Protein (CD4-DM140) catalog number: CD4-DM140 KACTUS Biosystems
