Biotinylated Human SIRP alpha V8 Protein (SRP-HM4V8B)
$472.50 – $1,575.00
KACTUS Biosystems Biotinylated Human SIRP alpha V8 Protein (SRP-HM4V8B) (catalog No. SRP-HM4V8B) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu31-Arg369(S44L, S50T, I52T, H54R, V57A).
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| Catalog No. | SRP-HM4V8B |
|---|---|
| Product Name | Biotinylated Human SIRP alpha V8 Protein (SRP-HM4V8B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | ATD50864.1 |
| Product Tag | C-His-Avi |
| Biotinylated | yes |
| Exact Sequence | Glu31-Arg369(S44L, S50T, I52T, H54R, V57A) |
| Molecular Weight | The protein has a predicted MW of 40.1 kDa. Due to glycosylation, the protein migrates to 52-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SRP-HM4V8B: Biotinylated Human SIRP alpha V8 Protein (SRP-HM4V8B)
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the “don´t eat me” signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction.
Please remember our product information: Biotinylated Human SIRP alpha V8 Protein (SRP-HM4V8B) catalog number: SRP-HM4V8B KACTUS Biosystems