Biotinylated Human Siglec-10 (R119A) Protein (SIG-HM411B)
$472.50 – $1,575.00
KACTUS Biosystems Biotinylated Human Siglec-10 (R119A) Protein (SIG-HM411B) (catalog No. SIG-HM411B) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Met17-Thr546.
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| Catalog No. | SIG-HM411B |
|---|---|
| Product Name | Biotinylated Human Siglec-10 (R119A) Protein (SIG-HM411B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | SLG2; SIGLEC10; MGC126774; PRO940 |
| Species | Human |
| Source | HEK293 |
| Accession | Q96LC7-1 |
| Product Tag | C-His-Avi |
| Biotinylated | yes |
| Exact Sequence | Met17-Thr546 |
| Molecular Weight | The protein has a predicted MW of 62.64 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in 20mM Tirs 150mM NaCl, 200mM L-arginine (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SIG-HM411B: Biotinylated Human Siglec-10 (R119A) Protein (SIG-HM411B)
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
Please remember our product information: Biotinylated Human Siglec-10 (R119A) Protein (SIG-HM411B) catalog number: SIG-HM411B KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
