Biotinylated Human HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)
$279.00 – $1,125.00
KACTUS Biosystems Biotinylated Human HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B) (catalog No. MHC-HM411B) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M) and CLGGLLTMV peptide.
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| Catalog No. | MHC-HM411B |
|---|---|
| Product Name | Biotinylated Human HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | MHC; RMF; LMP2; LMP-2; Macropain chain 7; Proteasome chain 7; PSMB9; RING12 |
| Species | Human |
| Source | HEK293 |
| Accession | A0A140T913(HLA-A*02:01)&P61769(B2M)&CLGGLLTMV |
| Product Tag | C-His-Avi |
| Biotinylated | yes |
| Exact Sequence | Gly25-Thr305(HLA-A*02:01),Ile21-Met119(B2M)and CLGGLLTMV peptide |
| Molecular Weight | The protein has a predicted MW of 50.3 kDa. Due to glycosylation, the protein migrates to 51-60 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
MHC-HM411B: Biotinylated Human HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B)
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that selectively inhibit the major catalytic subunit, LMP2, of the immunoproteasome,LMP2-rich cancer cells compared to LMP2-deficient cancer cells are more sensitive to growth inhibition by the LMP2-specific inhibitor, implicating an important role of LMP2 in regulating cell growth of malignant tumors that highly express LMP2.
Please remember our product information: Biotinylated Human HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein (MHC-HM411B) catalog number: MHC-HM411B KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |