Biotinylated Human Her2/ErbB2 Domain 4 Protein (HER-HM404B)
$472.50 – $1,575.00
KACTUS Biosystems Biotinylated Human Her2/ErbB2 Domain 4 Protein (HER-HM404B) (catalog No. HER-HM404B) is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Pro489-Cys630.
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| Catalog No. | HER-HM404B |
|---|---|
| Product Name | Biotinylated Human Her2/ErbB2 Domain 4 Protein (HER-HM404B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | P04626-1 |
| Product Tag | C-His-Avi |
| Biotinylated | yes |
| Exact Sequence | Pro489-Cys630 |
| Molecular Weight | The protein has a predicted MW of 18.5 kDa. Due to glycosylation, the protein migrates to 28-40 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
HER-HM404B: Biotinylated Human Her2/ErbB2 Domain 4 Protein (HER-HM404B)
ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kinase receptors. ErbB family members serve as receptors for the epidermal growth factor (EGF) family of growth factors.Upon ERBB2 activation, the MEMO1-RHOA-DIAPH1 signaling pathway elicits the phosphorylation and thus the inhibition of GSK3B at cell membrane. This prevents the phosphorylation of APC and CLASP2, allowing its association with the cell membrane.
Please remember our product information: Biotinylated Human Her2/ErbB2 Domain 4 Protein (HER-HM404B) catalog number: HER-HM404B KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
