Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B)
$283.50 – $945.00
KACTUS Biosystems Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B) (catalog No. SIG-CM110B) is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Asn552.
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| Catalog No. | SIG-CM110B |
|---|---|
| Product Name | Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Cynomolgus |
| Source | HEK293 |
| Accession | A0A2K5WBX8 |
| Product Tag | C-His |
| Biotinylated | yes |
| Exact Sequence | Thr17-Asn552 |
| Molecular Weight | The protein has a predicted MW of 59.90 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in 25mM MES, 150mM NaCl, 0.5M Arginine (pH 5.0). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SIG-CM110B: Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B)
Siglec-10 is a ligand for CD52, the target of the therapeutic monoclonal antibody Alemtuzumab. It is also reported to bind to Vascular adhesion protein 1 (VAP-1) and to the co-stimulatory molecule CD24 also known as HSA (Heat-stable antigen).Siglecs (sialic acid binding Ig-like lectins) are I-type lectins that belong to the immunoglobulin superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by a varying number of Ig-like C2-type domains. Siglecs 5-11 constitute the CD33/Siglec-3 related group, and are differentially expressed in the hematopoietic system.
Please remember our product information: Biotinylated Cynomolgus Siglec-10 Protein (Primary Amine Labeling) (SIG-CM110B) catalog number: SIG-CM110B KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |