α-Actin-1 (α-SMA) Rabbit mAb (A2235)

α-Actin-1 (α-SMA) Rabbit mAb (A2235)

α-Actin-1 (α-SMA) Rabbit mAb (A2235)

$148.00$548.00

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$148.00$548.00

Abclonal α-Actin-1 (α-SMA) Rabbit mAb (Catalog Number: A2235) encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity.

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Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Catalog No. A2235
Product Nameα-Actin-1 (α-SMA) Rabbit mAb (A2235)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms ACTA; ASMA; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; CFTD1; CFTDM; CMYP2A; CMYP2B; CMYP2C
Gene Name ACTA1
Protein Name ACTA1
Uniprot/Swissprot ID P68133
Gene ID 58
Clone ARC1912
Clonality Monoclonal
Source/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A2235: α-Actin-1 (α-SMA) Rabbit mAb

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause a variety of myopathies, including nemaline myopathy, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects with manifestations such as hypotonia.

Immunogen Information about α-Actin-1 (α-SMA) Rabbit mAb (A2235)

Immunogen:A synthetic peptide corresponding to a sequence within amino acids 278-377 of human α-Actin-1 (ACTA1) (P68133).
Sequence:ETTYNSIMKCDIDIRKDLYANNVMSGGTTMYPGIADRMQKEITALAPSTMKIKIIAPPERKYSVWIGGSILASLSTFQQMWITKQEYDEAGPSIVHRKCF
Gene ID:58
Swiss prot:P68133
Synonyms:ACTA; ACTA1; CFTD; MPFD; NEM1; NEM2; NEM3; SHPM; CFTD1; CFTDM; CMYP2A; CMYP2B; CMYP2C; α-Actin-1 (α-SMA)
Calculated MW:42kDa
Observed MW:42kDa

Images of α-Actin-1 (α-SMA) Rabbit mAb (A2235)

Western blot analysis of extracts from various s, using α-Actin-1 (α-SMA) Rabbit mAb (A2235) at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (AS014) at 1:10000 dilution.
Lysates/proteins: 25μg per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Basic Kit (RM00020).
Exposure time: 1s.

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using α-Actin-1 (ACTA1) Rabbit mAb (A2235) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of paraffin-embedded human kidney using α-Actin-1 (ACTA1) Rabbit mAb (A2235) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunohistochemistry analysis of paraffin-embedded human spleen using α-Actin-1 (ACTA1) Rabbit mAb (A2235) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.

Immunofluorescence analysis of rat skeletal muscle using α-Actin-1 (ACTA1) Rabbit mAb (A2235) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Immunofluorescence analysis of mouse skeletal muscle using α-Actin-1 (ACTA1) Rabbit mAb (A2235) at dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.

Please remember our product information: α-Actin-1 (α-SMA) Rabbit mAb (Catalog Number: A2235) Abclonal

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