ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)
$218.00 – $568.00
Abclonal ABflo® 647 Rabbit anti-Human CD45 mAb (Catalog Number: A22495) encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation.
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| Catalog No. | A22495 |
|---|---|
| Product Name | ABflo® 647 Rabbit anti-Human CD45 mAb (A22495) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105 |
| Gene Name | PTPRC |
| Protein Name | PTPRC |
| Uniprot/Swissprot ID | P08575-8 |
| Entrez GeneID | 5788 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | FC |
| Reactivity | Human |
| Conjugate | ABflo® 647. Ex:656nm. Em:670nm. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22495: ABflo® 647 Rabbit anti-Human CD45 mAb
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.
Immunogen Information about ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 26-577 of human CD45 (P08575).
Sequence：QSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTGVSSVQTPHLPTHADSQTPSAGTDTQTFSGSAANAKLNPTPGSNAISDVPGERSTASTFPTDPVSPLTTTLSLAHHSSAALPARTSNTTITANTSDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSK
Gene ID：5788
Swiss prot：P08575
Synonyms：LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Calculated MW：138kDa
Observed MW：Refer to figures
Images of ABflo® 647 Rabbit anti-Human CD45 mAb (A22495)
Flow cytometry: 1X10^6 293T cells (negative control, left) and Jurkat cells (right) were surface-stained with ABflo® 647 Rabbit anti-Human CD45 mAb (A22495, 2 μg/mL, orange line) or ABflo® 647 Rabbit IgG isotype control (A22070, 2 μg/mL, blue line). Non-fluorescently stained cells was used as blank control (red line).
Flow cytometry: 1X10^6 Jurkat cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, left) or ABflo® 647 Rabbit anti-Human CD45 mAb (A22495, 5 μl/Test, right).
Flow cytometry: 1X10^6 Human PBMC were surface-stained with ABflo® 647 Rabbit anti-Human CD45 mAb (A22495, 5 μl/Test, orange line) or ABflo® 647 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained Human PBMC was used as blank control (red line).
Flow cytometry: 1X10^6 Human PBMC cells were surface-stained with ABflo® 647 Rabbit IgG isotype control (A22070, 5 μl/Test, left) or ABflo® 647 Rabbit anti-Human CD45 mAb (A22495, 5 μl/Test, right).
Please remember our product information: ABflo® 647 Rabbit anti-Human CD45 mAb (Catalog Number: A22495) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μg, 25 μg, 50 μg |