ABflo® 488 Rabbit anti-Human Siglec-8 mAb (A22189)
$218.00 – $568.00
Abclonal ABflo® 488 Rabbit anti-Human Siglec-8 mAb (Catalog Number: A22189) Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells.
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| Catalog No. | A22189 |
|---|---|
| Product Name | ABflo® 488 Rabbit anti-Human Siglec-8 mAb (A22189) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | SAF2; SIGLEC-8; SIGLEC8L |
| Gene Name | SIGLEC8 |
| Protein Name | SIGLEC8 |
| Uniprot/Swissprot ID | Q9NYZ4 |
| Entrez GeneID | 27181 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | FC |
| Reactivity | Human |
| Conjugate | ABflo® 488. Ex:491nm. Em:516nm. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22189: ABflo® 488 Rabbit anti-Human Siglec-8 mAb
Sialic acid-binding immunoglobulin (Ig)-like lectins, or SIGLECs (e.g., CD33 (MIM 159590)), are a family of type 1 transmembrane proteins each having a unique expression pattern, mostly in hemopoietic cells. SIGLEC8 is a member of the CD33-like subgroup of SIGLECs, which are localized to 19q13.3-q13.4 and have 2 conserved cytoplasmic tyrosine-based motifs: an immunoreceptor tyrosine-based inhibitory motif, or ITIM (see MIM 604964), and a motif homologous to one identified in signaling lymphocyte activation molecule (SLAM; MIM 603492) that mediates an association with SLAM-associated protein (SAP; MIM 300490) (summarized by Foussias et al., 2000 [PubMed 11095983]).
Immunogen Information about ABflo® 488 Rabbit anti-Human Siglec-8 mAb (A22189)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 17-363 of human Siglec-8(NP_055257.2)
Sequence：MEGDRQYGDGYLLQVQELVTVQEGLCVHVPCSFSYPQDGWTDSDPVHGYWFRAGDRPYQDAPVATNNPDREVQAETQGRFQLLGDIWSNDCSLSIRDARKRDKGSYFFRLERGSMKWSYKSQLNYKTKQLSVFVTALTHRPDILILGTLESGHSRNLTCSVPWACKQGTPPMISWIGASVSSPGPTTARSSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTALGNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGSLTLCPSRSSNPGLLELPRVHVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAA
Gene ID：27181
Swiss prot：Q9NYZ4
Synonyms：SAF2; SIGLEC-8; SIGLEC8L
Calculated MW：44kDa/46kDa/54kDa
Observed MW：
Images of ABflo® 488 Rabbit anti-Human Siglec-8 mAb (A22189)
Flow cytometry:1X10^6 293F cells (negative control, left) and 293F(Transfection, right) cells were surface-stained with ABflo® 488 Rabbit anti-Human Siglec-8 mAb(A22189, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Please remember our product information: ABflo® 488 Rabbit anti-Human Siglec-8 mAb (Catalog Number: A22189) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μg, 25 μg, 50 μg |