ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (A22692)
$218.00 – $568.00
Abclonal ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (Catalog Number: A22692) encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein.
- Product Details
- Description
- Additional information
- More Offers
| Catalog No. | A22692 |
|---|---|
| Product Name | ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (A22692) |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324 |
| Gene Name | CDH1 |
| Protein Name | CDH1 |
| Uniprot/Swissprot ID | P12830 |
| Entrez GeneID | 999 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | FC |
| Reactivity | Human |
| Conjugate | ABflo® 488. Ex:491nm. Em:516nm. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
A22692: ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb
This gene encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. This gene is present in a gene cluster with other members of the cadherin family on chromosome 16.
Immunogen Information about ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (A22692)
Immunogen：Recombinant fusion protein containing a sequence corresponding to amino acids 155-707 of human E-Cadherin/CD324 (NP_004351.1).
Sequence：DWVIPPISCPENEKGPFPKNLVQIKSNKDKEGKVFYSITGQGADTPPVGVFIIERETGWLKVTEPLDRERIATYTLFSHAVSSNGNAVEDPMEILITVTDQNDNKPEFTQEVFKGSVMEGALPGTSVMEVTATDADDDVNTYNAAIAYTILSQDPELPDKNMFTINRNTGVISVVTTGLDRESFPTYTLVVQAADLQGEGLSTTATAVITVTDTNDNPPIFNPTTYKGQVPENEANVVITTLKVTDADAPNTPAWEAVYTILNDDGGQFVVTTNPVNNDGILKTAKGLDFEAKQQYILHVAVTNVVPFEVSLTTSTATVTVDVLDVNEAPIFVPPEKRVEVSEDFGVGQEITSYTAQEPDTFMEQKITYRIWRDTANWLEINPDTGAISTRAELDREDFEHVKNSTYTALIIATDNGSPVATGTGTLLLILSDVNDNAPIPEPRTIFFCERNPKPQVINIIDADLPPNTSPFTAELTHGASANWTIQYNDPTQESIILKPKMALEVGDYKINLKLMDNQNKDQVTTLEVSVCDCEGAAGVCRKAQPVEAGLQI
Gene ID：999
Swiss prot：P12830
Synonyms：UVO; CDHE; ECAD; LCAM; Arc-1; BCDS1; CD324
Calculated MW：90kDa/97kDa
Observed MW：90kDa/97kDa
Images of ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (A22692)
Flow cytometry:1X10^6 K-562 cells (negative control, Left) and A431 cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (A22692, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).
Flow cytometry:1X10^6 A431 cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (A22692, 5 μl/Test, right).
Please remember our product information: ABflo® 488 Rabbit anti-Human E-Cadherin/CD324 mAb (Catalog Number: A22692) Abclonal
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 μg, 25 μg, 50 μg |