ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (A23018)

ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (A23018)

ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (A23018)

$140.00$388.00

In stock

$140.00$388.00

Abclonal ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (Catalog Number: A23018) This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells.

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Catalog No. A23018
Product NameABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (A23018)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms K8; KO; CK8; CK-8; CYK8; K2C8; CARD2
Gene Name KRT8
Protein Name KRT8
Uniprot/Swissprot ID P05787
Entrez GeneID 3856
Clonality Monoclonal
Source/Host Rabbit
Applications FC(Intra)
Reactivity Human
Conjugate ABflo® 488. Ex:491nm. Em:516nm.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A23018: ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb

This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.

Immunogen Information about ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (A23018)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-483 of human Cytokeratin 8 (NP_002264.1).
Sequence:MSIRVTQKSYKVSTSGPRAFSSRSYTSGPGSRISSSSFSRVGSSNFRGGLGGGYGGASGMGGITAVTVNQSLLSPLVLEVDPNIQAVRTQEKEQIKTLNNKFASFIDKVRFLEQQNKMLETKWSLLQQQKTARSNMDNMFESYINNLRRQLETLGQEKLKLEAELGNMQGLVEDFKNKYEDEINKRTEMENEFVLIKKDVDEAYMNKVELESRLEGLTDEINFLRQLYEEEIRELQSQISDTSVVLSMDNSRSLDMDSIIAEVKAQYEDIANRSRAEAESMYQIKYEELQSLAGKHGDDLRRTKTEISEMNRNISRLQAEIEGLKGQRASLEAAIADAEQRGELAIKDANAKLSELEAALQRAKQDMARQLREYQELMNVKLALDIEIATYRKLLEGEESRLESGMQNMSIHTKTTSGYAGGLSSAYGGLTSPGLSYSLGSSFGSGAGSSSFSRTSSSRAVVVKKIETRDGKLVSESSDVLPK
Gene ID:3856
Swiss prot:P05787
Synonyms:K8; KO; CK8; CK-8; CYK8; K2C8; CARD2
Calculated MW:53kDa/56kDa
Observed MW:Refer to figures

Images of ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (A23018)

Flow cytometry:1X10^6 Jurkat cells (negative control, Left) and HeLa cells (Right) were intracellularly-stained with ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb(A23018, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells was used as blank control (red line).

Flow cytometry:1X10^6 HeLa cells were intracellularly-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb(A23018, 5 μl/Test, right).

Please remember our product information: ABflo® 488 Rabbit anti-Human Cytokeratin 8 mAb (Catalog Number: A23018) Abclonal

Additional information

Ship from Country

USA

Size

100 μg, 25 μg, 50 μg

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