ABflo® 488 Rabbit anti-Human CD45RA mAb (A22569)

ABflo® 488 Rabbit anti-Human CD45RA mAb (A22569)

ABflo® 488 Rabbit anti-Human CD45RA mAb (A22569)

$218.00$568.00

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$218.00$568.00

Abclonal ABflo® 488 Rabbit anti-Human CD45RA mAb (Catalog Number: A22569) encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.

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Catalog No. A22569
Product NameABflo® 488 Rabbit anti-Human CD45RA mAb (A22569)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Gene Name PTPRC
Protein Name PTPRC
Uniprot/Swissprot ID P08575-8
Entrez GeneID 5788
Clonality Monoclonal
Source/Host Rabbit
Applications FC
Reactivity Human
Conjugate ABflo® 488. Ex:491nm. Em:516nm.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A22569: ABflo® 488 Rabbit anti-Human CD45RA mAb

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported.

Immunogen Information about ABflo® 488 Rabbit anti-Human CD45RA mAb (A22569)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 26-482 of human CD45RA (P08575-8).
Sequence:QSPTPSPTGLTTAKMPSVPLSSDPLPTHTTAFSPASTFERENDFSETTTSLSPDNTSTQVSPDSLDNASAFNTTDAYLNASETTTLSPSGSAVISTTTIATTPSKPTCDEKYANITVDYLYNKETKLFTAKLNVNENVECGNNTCTNNEVHNLTECKNASVSISHNSCTAPDKTLILDVPPGVEKFQLHDCTQVEKADTTICLKWKNIETFTCDTQNITYRFQCGNMIFDNKEIKLENLEPEHEYKCDSEILYNNHKFTNASKIIKTDFGSPGEPQIIFCRSEAAHQGVITWNPPQRSFHNFTLCYIKETEKDCLNLDKNLIKYDLQNLKPYTKYVLSLHAYIIAKVQRNGSAAMCHFTTKSAPPSQVWNMTVSMTSDNSMHVKCRPPRDRNGPHERYHLEVEAGNTLVRNESHKNCDFRVKDLQYSTDYTFKAYFHNGDYPGEPFILHHSTSYNSK
Gene ID:5788
Swiss prot:P08575-8
Synonyms:LCA; LY5; B220; CD45; L-CA; T200; CD45R; GP180; IMD105
Calculated MW:138kDa
Observed MW:

Images of ABflo® 488 Rabbit anti-Human CD45RA mAb (A22569)

Flow cytometry:1X10^6 293T cells (negative control, left) and Daudi cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human CD45RA mAb(A22569, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).

Flow cytometry:1X10^6 Daudi cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human CD45RA mAb(A22569, 5 μl/Test, right).

Please remember our product information: ABflo® 488 Rabbit anti-Human CD45RA mAb (Catalog Number: A22569) Abclonal

Additional information

Ship from Country

USA

Size

100 μg, 25 μg, 50 μg

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