ABflo® 488 Rabbit anti-Human AXL mAb (A22502)

ABflo® 488 Rabbit anti-Human AXL mAb (A22502)

ABflo® 488 Rabbit anti-Human AXL mAb (A22502)

$290.00$768.00

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$290.00$768.00

Abclonal ABflo® 488 Rabbit anti-Human AXL mAb (Catalog Number: A22502) encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily.

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Catalog No. A22502
Product NameABflo® 488 Rabbit anti-Human AXL mAb (A22502)
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms ARK; UFO; JTK11; Tyro7
Gene Name AXL
Protein Name AXL
Uniprot/Swissprot ID P30530
Entrez GeneID 558
Clonality Monoclonal
Source/Host Rabbit
Applications FC
Reactivity Human
Conjugate ABflo® 488. Ex:491nm. Em:516nm.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

A22502: ABflo® 488 Rabbit anti-Human AXL mAb

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. The encoded protein acts as a host cell receptor for multiple viruses, including Marburg, Ebola and Lassa viruses and is a candidate receptor for the SARS-CoV2 virus.

Immunogen Information about ABflo® 488 Rabbit anti-Human AXL mAb (A22502)

Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 33-449 of human AXL (NP_068713.2).
Sequence:EESPFVGNPGNITGARGLTGTLRCQLQVQGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVFLGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDAVPLATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTELEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLHPHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPLQGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLPVPLEAWRPGQAQPVHQLVKEPSTPAFSWP
Gene ID:558
Swiss prot:P30530
Synonyms:ARK; UFO; JTK11; Tyro7
Calculated MW:98kDa
Observed MW:

Images of ABflo® 488 Rabbit anti-Human AXL mAb (A22502)

Flow cytometry:1X10^6 Jurkat cells (negative control, left) and U-251 MG cells (right) were surface-stained with ABflo® 488 Rabbit anti-Human AXL mAb(A22502, 5 μl/Test, orange line) or ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, blue line). Non-fluorescently stained cells were used as blank control (red line).

Flow cytometry:1X10^6 U-251MG cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human AXL mAb(A22502, 5 μl/Test, right).

Flow cytometry:1X10^6 Human PBMC cells were surface-stained with ABflo® 488 Rabbit IgG isotype control (A22069, 5 μl/Test, left) or ABflo® 488 Rabbit anti-Human AXL mAb(A22502, 5 μl/Test, right).

Please remember our product information: ABflo® 488 Rabbit anti-Human AXL mAb (Catalog Number: A22502) Abclonal

Additional information

Ship from Country

USA

Size

100 μg, 25 μg, 50 μg

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