14-3-3 epsilon Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

14-3-3 epsilon Rabbit mAb

$148.00$548.00

In stock

$148.00$548.00

MDS; HEL2; MDCR; KCIP-1; 14-3-3E

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SKU: A4933 Categories: ,
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Phone: 1-617-401-8149
Fax: 1-617-606-5019
Email: message@sydlabs.com
Catalog No. A4933
Product Name14-3-3 epsilon Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms MDS; HEL2; MDCR; KCIP-1; 14-3-3E
Gene Name YWHAE
Protein Name YWHAE
Uniprot/Swissprot ID P62258
Gene ID 7531
Clone ARC1222
Clonality Monoclonal
Source/Host Rabbit
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.

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