Troponin I2 (TNNI2) Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

Troponin I2 (TNNI2) Rabbit mAb

$148.00$548.00

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$148.00$548.00

DA2B; FSSV; DA2B1; fsTnI; AMCD2B

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SKU: A4740
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Catalog No. A4740
Product NameTroponin I2 (TNNI2) Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms DA2B; FSSV; DA2B1; fsTnI; AMCD2B
Gene Name TNNI2
Protein Name TNNI2
Uniprot/Swissprot ID P48788
Entrez GeneID 7136
Clone ARC1114
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IF/ICC
Reactivity Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a fast-twitch skeletal muscle protein, a member of the troponin I gene family, and a component of the troponin complex including troponin T, troponin C and troponin I subunits. The troponin complex, along with tropomyosin, is responsible for the calcium-dependent regulation of striated muscle contraction. Mouse studies show that this component is also present in vascular smooth muscle and may play a role in regulation of smooth muscle function. In addition to muscle tissues, this protein is found in corneal epithelium, cartilage where it is an inhibitor of angiogenesis to inhibit tumor growth and metastasis, and mammary gland where it functions as a co-activator of estrogen receptor-related receptor alpha. This protein also suppresses tumor growth in human ovarian carcinoma. Mutations in this gene cause myopathy and distal arthrogryposis type 2B. Alternatively spliced transcript variants have been found for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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