TAK1 Rabbit mAb
$148.00 – $548.00
CSCF; FMD2; TAK1; MEKK7; TGF1a
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| Catalog No. | A19077 |
|---|---|
| Product Name | TAK1 Rabbit mAb |
| Supplier Name | ABclonal, Inc. |
| Brand Name | Abclonal |
| Synonyms | CSCF; FMD2; TAK1; MEKK7; TGF1a |
| Gene Name | MAP3K7 |
| Protein Name | MAP3K7 |
| Uniprot/Swissprot ID | O43318 |
| Entrez GeneID | 6885 |
| Clone | ARC0413 |
| Clonality | Monoclonal |
| Source/Host | Rabbit |
| Applications | WB, IP |
| Reactivity | Human, Mouse |
| Conjugate | Unconjugated |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
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