SOCS2 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

SOCS2 Rabbit mAb

$148.00$548.00

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$148.00$548.00

CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2

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SKU: A9190
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Catalog No. A9190
Product NameSOCS2 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms CIS2; SSI2; Cish2; SSI-2; SOCS-2; STATI2
Gene Name SOCS2
Protein Name SOCS2
Uniprot/Swissprot ID O14508
Entrez GeneID 8835
Clone ARC1470
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IHC-P, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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