Smad4 DPC4 Monoclonal Antibody
$350.00
Conditions of optimal Smad4 DPC4 monoclonal antibody performance should be determined experimentally by the investigator.
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| Catalog No. | PA000086-MA1089 |
|---|---|
| Product Name | Smad4 DPC4 Monoclonal Antibody |
| Supplier Name | Syd Labs, Inc. |
| Brand Name | Syd Labs |
| Synonyms | DPC4 Antibody |
| Clone | IMD-89. |
| Isotype | Mouse IgG1. |
| Specificity/Sensitivity | Human. No cross reactivity with other proteins. |
| Reactivity | Human. |
| Immunogen | Recombinant human Smad4 (DPC4). |
| Purification | Purified by the goat anti-mouse IgG affinity chromatography. |
| Form Of Antibody | Lyophilized from 1.2% sodium acetate, with 2 mg BSA and 0.01 mg NaN3 as preservative. |
| Stability & Storage | Stable for 1 year at -20°C and 3 months at 4°C. For maximum recovery of the product, centrifuge the original vial after thawing and before removing the cap. Aliquot to avoid repeated freezing and thawing. |
| Note | Conditions of optimal SMAD4 antibody performance should be determined experimentally by the investigator. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PA000086-MA1089: Smad4 DPC4 Monoclonal Antibody
Background
SMAD4 plays a pivotal role in signal transduction of the transforming growth factor beta superfamily cytokines by mediating transcriptional activation of target genes. Smad4 signalling in T cells is required for suppression of gastrointestinal cancer. Mutational inactivation of SMAD4 causes TGF-beta unresponsiveness and gave a basis for understanding the physiologic role of this gene in tumorigenesis. Mutations in DPC4 (SMAD4) cause juvenile polyposis syndrome, but only account for a minority of cases.
Other SMAD4 Antibodies:
Smad4 Polyclonal Antibody
Smad4 Polyclonal Antibody
Smad4 Polyclonal Antibody
SMAD4 Proteins:
Recombinant Human SMAD4 protein
Recombinant Human SMAD4 protein
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug |
