SARS-CoV-2 Spike RBD (Delta plus AY.1/AY.2) Protein (DP1-VM1BD)
$337.50 – $1,125.00
KACTUS Biosystems SARS-CoV-2 Spike RBD (Delta plus AY.1/AY.2) Protein (DP1-VM1BD) (catalog No. DP1-VM1BD) is expressed from HEK293 with His tag at the C-Terminus.It contains Arg319-Phe541(K417N, L452R, T478K).
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| Catalog No. | DP1-VM1BD |
|---|---|
| Product Name | SARS-CoV-2 Spike RBD (Delta plus AY.1/AY.2) Protein (DP1-VM1BD) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | SARS-COV-2 |
| Source | HEK293 |
| Accession | QHD43416.1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Arg319-Phe541(K417N, L452R, T478K) |
| Molecular Weight | The protein has a predicted MW of 26.25 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
DP1-VM1BD: SARS-CoV-2 Spike RBD (Delta plus AY.1/AY.2) Protein (DP1-VM1BD)
The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein.
Please remember our product information: SARS-CoV-2 Spike RBD (Delta plus AY.1/AY.2) Protein (DP1-VM1BD) catalog number: DP1-VM1BD KACTUS Biosystems