Phospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb

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Phospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb

$148.00$548.00

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$148.00$548.00

PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1

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SKU: AP1340
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Catalog No. AP1340
Product NamePhospho-PLC gamma 1 (PLCG1)-Y783 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms PLC1; NCKAP3; PLC-II; PLC148; PLCgamma1
Gene Name PLCG1
Protein Name PLCG1
Uniprot/Swissprot ID P19174
Entrez GeneID 5335
Clone ARC54936
Clonality Monoclonal
Source/Host Rabbit
Applications WB
Reactivity Mouse
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of receptor-mediated tyrosine kinase activators. For example, when activated by SRC, the encoded protein causes the Ras guanine nucleotide exchange factor RasGRP1 to translocate to the Golgi, where it activates Ras. Also, this protein has been shown to be a major substrate for heparin-binding growth factor 1 (acidic fibroblast growth factor)-activated tyrosine kinase. Two transcript variants encoding different isoforms have been found for this gene.

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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