Mouse Tim-3/HAVCR2 Protein (TIM-MM131)
$310.50 – $1,035.00
KACTUS Biosystems Mouse Tim-3/HAVCR2 Protein (TIM-MM131) (catalog No. TIM-MM131) is expressed from HEK293 with His tag at the C-Terminus.It contains Leu22-Arg191.
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| Catalog No. | TIM-MM131 |
|---|---|
| Product Name | Mouse Tim-3/HAVCR2 Protein (TIM-MM131) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | CD366; TIM3; TIM-3; TIMD-3; TIM 3; FLJ14428; HAVCR2; KIM3 |
| Species | Mouse |
| Source | HEK293 |
| Accession | Q8VIM0-1 |
| Product Tag | C-His |
| Biotinylated | no |
| Exact Sequence | Leu22-Arg191 |
| Molecular Weight | The protein has a predicted MW of 19.9 kDa, Due to glycosylation, the protein migrates to 40-68 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.； -20 to -80°C for 3-6 months in unopened state after reconstitution.； 2-8°C for 2-7 days after reconstitution.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
TIM-MM131: Mouse Tim-3/HAVCR2 Protein (TIM-MM131)
Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene.TIM3 is an immune checkpoint and together with other inhibitory receptors including programmed cell death protein 1 (PD-1) and lymphocyte activation gene 3 protein (LAG3) mediate the CD8 T-cell exhaustion. TIM3 has also been shown as a CD4 Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.
Please remember our product information: Mouse Tim-3/HAVCR2 Protein (TIM-MM131) catalog number: TIM-MM131 KACTUS Biosystems
