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Mouse Kallikrein 5/KLK5 Protein (KLK-MM105)

Mouse Kallikrein 5/KLK5 Protein (KLK-MM105)

Mouse Kallikrein 5/KLK5 Protein (KLK-MM105)

$243.00$810.00

In stock

$243.00$810.00

KACTUS Biosystems Mouse Kallikrein 5/KLK5 Protein (KLK-MM105) (catalog No. KLK-MM105) is expressed from HEK293 with His tag at the C-Terminus.It contains Gly30-Asn293.

SKU: KLK-MM105
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Catalog No. KLK-MM105
Product NameMouse Kallikrein 5/KLK5 Protein (KLK-MM105)
Supplier Name KACTUS Biosystems
Brand Name KACTUS Biosystems
Synonyms Kallikrein c; Klnc; KLK5; KLKL2; KLK-L2; SCTE
Species Mouse
Source HEK293
Accession Q9D140
Product Tag C-His
Biotinylated no
Exact Sequence Gly30-Asn293
Molecular Weight The protein has a predicted MW of 29.9 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Form Lyophilized
Formulation Lyophilized from 0.22μm filtered solution in 20mM NaAc, 150mM NaCl (pH 5.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in 20mM NaAc, 150mM NaCl (pH 5.0).
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per μg by the LAL method.
Shipping Shipped at ambient temperature.
Stability & Storage '-20 to -80°C for 12 months as supplied from date of receipt.;-20 to -80°C for 3-6 months in unopened state after reconstitution.;2-8°C for 2-7 days after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

KLK-MM105: Mouse Kallikrein 5/KLK5 Protein (KLK-MM105)

The inhibition of kallikrein 5 (KLK5) has been identified as a potential strategy for treatment of the genetic skin disorder Netherton syndrome, in which loss-of-function mutations in the SPINK5 gene lead to down-regulation of the endogenous inhibitor LEKTI-1 and profound skin-barrier defects with severe allergic manifestations. To aid in the development of a medicine for this target, an X-ray crystallographic system was developed to facilitate fragment-guided chemistry and knowledge-based drug-discovery approaches.

Please remember our product information: Mouse Kallikrein 5/KLK5 Protein (KLK-MM105) catalog number: KLK-MM105 KACTUS Biosystems

Additional information

Ship from Country

USA

Size

100 ug, 500 ug

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