Catalog No.	IGF-MM41R
Product Name	Mouse IGF1R/CD221 Protein (IGF-MM41R)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Species	Mouse
Source	HEK293
Accession	Q60751
Product Tag	C-His
Biotinylated	no
Exact Sequence	Glu31-His936
Molecular Weight	The protein has a predicted MW of 80.72 kDa (alpha subunit) and 23.0 kDa (beta subunit). Due to furin cleavage and glycosylation, the protein migrates to 110-140 kDa(alpha subunit) and 50-65 kDa(beta subunit) based on Tris-Bis PAGE result.
Form	Lyophilized
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity	> 95% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped at ambient temperature.
Stability & Storage	'-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

IGF-MM41R: Mouse IGF1R/CD221 Protein (IGF-MM41R)

The type 1 IGF receptor (IGF1R) is a transmembrane tyrosine kinase that is frequently overexpressed by tumours, and mediates proliferation and apoptosis protection. IGF signalling also influences hypoxia signalling, protease secretion, tumour cell motility and adhesion, and thus can affect the propensity for invasion and metastasis. Therefore, the IGF1R is now an attractive anti-cancer treatment target.

Please remember our product information: Mouse IGF1R/CD221 Protein (IGF-MM41R) catalog number: IGF-MM41R KACTUS Biosystems

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