[KO Validated] PHD2/EGLN1 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

[KO Validated] PHD2/EGLN1 Rabbit mAb

$148.00$548.00

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$148.00$548.00

HPH2; PHD2; SM20; ECYT3; HALAH; HPH-2; HIFPH2; ZMYND6; C1orf12; HIF-PH2

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SKU: A21252
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Catalog No. A21252
Product Name[KO Validated] PHD2/EGLN1 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms HPH2; PHD2; SM20; ECYT3; HALAH; HPH-2; HIFPH2; ZMYND6; C1orf12; HIF-PH2
Gene Name EGLN1
Protein Name EGLN1
Uniprot/Swissprot ID Q9GZT9
Entrez GeneID 54583
Clone ARC52542
Clonality Monoclonal
Source/Host Rabbit
Applications WB
Reactivity Human
Conjugate Unconjugated
Note Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

The protein encoded by this gene catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. HIF is a transcriptional complex that plays a central role in mammalian oxygen homeostasis. This protein functions as a cellular oxygen sensor, and under normal oxygen concentration, modification by prolyl hydroxylation is a key regulatory event that targets HIF subunits for proteasomal destruction via the von Hippel-Lindau ubiquitylation complex. Mutations in this gene are associated with erythrocytosis familial type 3 (ECYT3).

Additional information

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USA

Size

20 ul, 100 ul, 200 ul, 50 ul

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