[KO Validated] FGF2 Rabbit mAb

Phospho-Myosin Light Chain 2-S19 Rabbit mAbPhospho-Myosin Light Chain 2-S19 Rabbit mAb

[KO Validated] FGF2 Rabbit mAb

$148.00$548.00

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$148.00$548.00

BFGF; FGFB; FGF-2; HBGF-2

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Catalog No. A11488
Product Name[KO Validated] FGF2 Rabbit mAb
Supplier Name ABclonal, Inc.
Brand Name Abclonal
Synonyms BFGF; FGFB; FGF-2; HBGF-2
Gene Name FGF2
Protein Name FGF2
Uniprot/Swissprot ID P09038
Entrez GeneID 2247
Clone ARC0618
Clonality Monoclonal
Source/Host Rabbit
Applications WB, IHC-P, IF/ICC
Reactivity Human, Mouse, Rat
Conjugate Unconjugated
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Description

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

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