Human SIGIRR Protein (SGR-HM201)
$216.00 – $720.00
KACTUS Biosystems Human SIGIRR Protein (SGR-HM201) (catalog No. SGR-HM201) is expressed from HEK293 with hFc tag at the C-terminal.It contains Met1-His118.
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| Catalog No. | SGR-HM201 |
|---|---|
| Product Name | Human SIGIRR Protein (SGR-HM201) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Species | Human |
| Source | HEK293 |
| Accession | Q6IA17-1 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Met1-His118 |
| Molecular Weight | The protein has a predicted MW of 39.29 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Tris-Bis PAGE result. |
| Form | Liquid |
| Formulation | Supplied as 0.22μm filtered solution in PBS (pH 7.4). |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped with dry ice. |
| Stability & Storage | Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
SGR-HM201: Human SIGIRR Protein (SGR-HM201)
TIR8, also known as single Ig IL-1-related receptor, is a member of the IL-1 receptor/Toll-like receptor (TLR) superfamily, which acts as an intracellular decoy for components of the signaling pathway. Structurally, it is characterized by a single extracellular Ig domain, an intracellular TIR domain and 95-aa cytoplasmic tail. Recently, TIR8 was shown to inhibit NF-B activation by members of the IL-1/TLR family. The inhibitory activity of TIR8 was associated with trapping of TRAF6 and IRAK1.
Please remember our product information: Human SIGIRR Protein (SGR-HM201) catalog number: SGR-HM201 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |