Human PSMP Protein (PSM-HM201)
$243.00 – $810.00
KACTUS Biosystems Human PSMP Protein (PSM-HM201) (catalog No. PSM-HM201) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Lys37-Ser139.
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| Catalog No. | PSM-HM201 |
|---|---|
| Product Name | Human PSMP Protein (PSM-HM201) |
| Supplier Name | KACTUS Biosystems |
| Brand Name | KACTUS Biosystems |
| Synonyms | Msmp; Psmp |
| Species | Human |
| Source | HEK293 |
| Accession | Q1L6U9 |
| Product Tag | C-hFc |
| Biotinylated | no |
| Exact Sequence | Lys37-Ser139 |
| Molecular Weight | The protein has a predicted MW of 37.9 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result. |
| Form | Lyophilized |
| Formulation | Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per μg by the LAL method. |
| Shipping | Shipped at ambient temperature. |
| Stability & Storage | '-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
| Note | Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com. |
| Order Offline | Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com |
Description
PSM-HM201: Human PSMP Protein (PSM-HM201)
PC3-secreted microprotein (PSMP)/microseminoprotein (MSMP) is a novel chemotactic cytokine and its receptor is CCR2. PSMP was highly expressed in fibrotic/cirrhotic tissues from patients with different etiologies of liver disease and in the 3 experimental mouse models of fibrosis. Damage-associated molecular pattern molecules HMGB-1 and IL-33 induced hepatocytes to produce PSMP. PSMP promotes liver fibrosis through inflammatory macrophage infiltration, polarization and production of proinflammatory cytokines, as well as direct activation of hepatic stellate cells via its receptor CCR2.
Please remember our product information: Human PSMP Protein (PSM-HM201) catalog number: PSM-HM201 KACTUS Biosystems
Additional information
| Ship from Country | USA |
|---|---|
| Size | 100 ug, 500 ug |
