Human PCSK9 Protein (PCS-HM190)

Catalog No.	PCS-HM190
Product Name	Human PCSK9 Protein (PCS-HM190)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Synonyms	PC9; PCSK9; FH3; HCHOLA3; LDLCQ1; NARC-1
Species	Human
Source	HEK293
Accession	Q8NBP7-1
Product Tag	C-His
Biotinylated	no
Exact Sequence	Gln31-Gln692
Molecular Weight	Due to autocatalytic cleavage, the protein release the pro-form (59 kDa) and mature form (14 kDa). Due to glycosylation, the protein migrates to 65-68 kDa (pro-form) and 15kDa (mature form) based on Tris-Bis PAGE result.
Form	Liquid
Formulation	Supplied as 0.22μm filtered solution in 20mM PB, 300mM NaCl, 10% Glycerol (pH 7.4).
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped with dry ice.
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

PCS-HM190: Human PCSK9 Protein (PCS-HM190)

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is an enzyme encoded by the PCSK9 gene in humans on chromosome 1.The first two PCSK9 inhibitors, alirocumab and evolocumab, were approved as once every two week injections, by the U.S. Food and Drug Administration in 2015 for lowering LDL-particle concentrations when statins and other drugs were not sufficiently effective or poorly tolerated.

Please remember our product information: Human PCSK9 Protein (PCS-HM190) catalog number: PCS-HM190 KACTUS Biosystems

Additional information

Ship from Country	USA
Size	100 ug, 500 ug

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