Catalog No.	OGC-HM10R
Product Name	Human OSMR&GP130 Protein (OGC-HM10R)
Supplier Name	KACTUS Biosystems
Brand Name	KACTUS Biosystems
Species	Human
Source	HEK293
Accession	Q99650-1(OSMR)&P40189-1(GP130)
Product Tag	C-His-Flag
Biotinylated	no
Exact Sequence	Glu28-Met740(OSMR) & Glu23-Glu619(GP130)
Molecular Weight	The protein has a predicted MW of 82.2 kDa(OSMR) and 68.83 kDa(GP130). Due to glycosylation, the protein migrates to 100-140 kDa based on Tris-Bis PAGE result.
Form	Lyophilized
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per μg by the LAL method.
Shipping	Shipped at ambient temperature.
Stability & Storage	'-20 to -80°C for 12 months as supplied from date of receipt.；-20 to -80°C for 3-6 months in unopened state after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Note	Products will be shipped from the warehouse in Massachusetts. Promotion is running from time to time. Welcome to send a request for quote to message@sydlabs.com.
Order Offline	Syd Labs, Inc. 4 Avenue E, Hopkinton, MA 01748 USA. Phone: 1-617-401-8149 Fax: 1-617-606-5019 Email: message@sydlabs.com

Description

OGC-HM10R: Human OSMR&GP130 Protein (OGC-HM10R)

OSMR&gp130 is a type II receptor for OSM in humans. OSM can alternatively bind to a heterodimer of gp130 and LIF-R or of gp130 and OSMR (OSM receptor). On the basis of in vitro studies, the OSM ligand recruits a broader array of cell signaling pathways than most gp130 cytokines. OSMR and gp130 chains are widely expressed in connective tissue cells and tumor cells.

Please remember our product information: Human OSMR&GP130 Protein (OGC-HM10R) catalog number: OGC-HM10R KACTUS Biosystems

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